Food sources include turkey, chicken, pumpkin seeds, spinach, milk, and bananas. Be careful not to confuse 5-HTP with 5-hydroxytryptamine 5-HT , the chemical name for the neurotransmitter serotonin. Always exercise caution when buying this or any supplement. Supplements haven't been tested for safety and due to the fact that dietary supplements are largely unregulated, the content of some products may differ from what is specified on the product label.
Also keep in mind that the safety of supplements in pregnant women, nursing mothers, children, and those with medical conditions or who are taking medications has not been established.
You can get tips on using supplements, but if you're considering the use of 5-HTP supplements, talk with your primary care provider first. Self-treating a condition and avoiding or delaying standard care may have serious consequences. Everything feels more challenging when you're dealing with depression. Get our free guide when you sign up for our newsletter. Neuropsychiatr Dis Treat.
A functional-dimensional approach to depression: serotonin deficiency as a target syndrome in a comparison of 5-hydroxytryptophan and fluvoxamine. Tryptophan and 5-hydroxytryptophan for depression. Cochrane Database Syst Rev.
Eur Neurol. Comparison of the effect of 5-hydroxytryptophan and propranolol in the interval treatment of migraine. Schweiz Med Wochenschr. Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. J Int Med Res. Centers for Disease Control and Prevention.
Updated May 2, Trends Pharmacol Sci. For some people, chronic panic attacks are the result of low serotonin. Even for those with general feelings of stress, 5-HTP can be beneficial. One study looked at the effects of 5-HTP supplements in young people who did not suffer from depression but had high levels of romantic stress. Out of the 15 participants, all experienced reduced anxiety after 6 weeks of taking 5-HTP.
In one study , women who took 5-HTP for just 2 weeks lost an average of 4. Combining it with 5-HTP likely has a synergistic effect In fact, several animal and insect studies suggest that 5-HTP improves sleep quality and that the effect is greater when combined with GABA 38 , While these results are promising, the lack of human-based studies makes it difficult to recommend 5-HTP for improving sleep quality, especially when it is used in isolation. Some people may experience nausea, diarrhea, vomiting and stomach pain when taking 5-HTP supplements.
These side effects are dose-dependent, meaning they get worse when increasing your dose To minimize these side effects, start with a dose of 50— mg two times per day and increase to the appropriate dose over a two-week period Some medications increase serotonin production.
Combining these medications with 5-HTP may cause dangerous serotonin levels in your body. This is called serotonin syndrome, a potentially life-threatening condition Since 5-HTP may also promote sleep, taking it with prescription sedative medications, such as Klonopin, Ativan or Ambien, may cause too much sleepiness. Due to the potential for negative interactions with other medications, consult your doctor or pharmacist before taking 5-HTP supplements.
These are third-party companies that ensure supplements contain what they claim on the label, without impurities. Some people may experience side effects when taking 5-HTP supplements. These supplements are not the same as L-tryptophan supplements , which may also increase serotonin levels L-tryptophan is an essential amino acid found in protein-rich foods, such as dairy products, poultry, meat, chickpeas and soybeans.
On the other hand, 5-HTP is not present in foods and can only be added to your diet through a supplement Your body converts 5-HTP into serotonin, a substance that regulates appetite, pain sensations and sleep. Higher serotonin levels may provide many benefits, such as promoting weight loss, improving the symptoms of depression and fibromyalgia, decreasing the frequency of migraine attacks and helping you sleep better.
Minor side effects have been linked to 5-HTP, but they can be minimized by starting with smaller doses and increasing the dosage gradually. Some supplements can have powerful effects.
Here is a list of 4 natural supplements that are just as effective as pharmaceutical drugs. Researchers have studied numerous herbs, supplements, and vitamins to determine if they can benefit people with depression.
Learn what they've found. DeBenedittis G, Massei R. Serotonin precursors in chronic primary headache. A double-blind cross-over study with Lhydroxytryptophan vs. J Neurosurg Sci. Zolpidem-associated hallucinations and serotonin reuptake inhibition: a possible interaction.
J Toxicol Clin Toxicol. Freedman RR. Treatment of menopausal hot flashes with 5-hydroxytryptophan. Sumatriptan contraindications and the serotonin syndrome. Ann Pharmacother. Hum Psychopharmacol. Second-tier natural antidepressants: Review and critique. J Affect Disord. Comparative study of efficacy of Ihydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
Asian J Psychiatr. Co-administration of fluoxetine and sumatriptan: the Canadian experience. Acta Psychiatr Scand. Development of pseudobullous morphea and scleroderma-like illness during therapy with Lhydroxytryptophan and carbidopa. J Am Acad Dermatol. Juhl JH. Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a day open study. Visceral hypersensitivity in irritable bowel syndrome: evidence for involvement of serotonin metabolism--a preliminary study. Neurogastroenterol Motil.
Possible serotonin syndrome associated with tramadol and sertraline coadministration. Meyers S. Use of neurotransmitter precursors for treatment of depression. Perry NK. Venlafaxine-induced serotonin syndrome with relapse following amitripyline.
Postgrad Med J. Puttini PS, Caruso I. Primary fibromyalgia and 5-hydroxy-L-tryptophan: a day open study. Uptake and utilization of [betac] 5-hydroxytryptophan 5-HTP in human brain studied by positron emission tomography.
0コメント